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Article

(CCTTT)n repeat polymorphism in the NOS2 gene promoter is associated with atopy.

The Journal of allergy and clinical immunology - 1 Nov 2001

Konno S, Hizawa N, Yamaguchi E, Jinushi E, Nishimura M

Abstract excerpt

BACKGROUND: Several studies have shown that nitric oxide (NO) plays a role in the regulation of the T(H)1/T(H)2 balance, indicating the potential for NO to contribute to the development of atopy and several other allergic diseases, including bronchial asthma. NO synthase 2 (NOS2) is critically involved in the synthesis of NO during several inflammatory states, and the gene encoding NOS2 is located at chromosome...

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Topics

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Share to Asthma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nitric Oxide Synthase

Share to Nitric Oxide Synthase Type II

Share to Odds Ratio

Share to Promoter Regions, Genetic

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 11692109
DOI: 10.1067/mai.2001.119030

Genes

NOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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(CCTTT)n repeat polymorphism in the NOS2 gene promoter is associated with atopy.PMID 11692109Read ↗

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Nitric Oxide Synthase 2 Promoter Polymorphism Is a Risk Factor for Allergic Asthma in Children.Semantic proximity Read ↗

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The effects of NOS1 gene on asthma and total IgE levels in Taiwanese children, and the interactions with environmental factors.Semantic proximity Read ↗

Variants of NOS1, NOS2, and NOS3 genes in asthmatics.Semantic proximity Read ↗

Analysis of the inducible nitric oxide synthase gene polymorphisms in Czech patients with atopic diseases.Semantic proximity Read ↗

Single nucleotide polymorphisms in the NOS2 and NOS3 genes are associated with exhaled nitric oxide.Semantic proximity Read ↗

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NOS2A promoter (CCTTT)n association with TB lacks independent functional correlation amongst Indians.Semantic proximity Read ↗

NOS1 polymorphism is associated with atopy but not exhaled nitric oxide levels in healthy children.Semantic proximity Read ↗

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