Article
A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate.
Pharmacogenetics and genomics - 1 Jul 2007
Thompson Miles D, Capra Valérie, Takasaki Jun, Maresca Giovanna, Rovati G Enrico, Slutsky Aurther S, Lilly Craig, Zamel Noe, McIntyre Burnham W, Cole David E, Siminovitch Katherine A
Abstract excerpt
Atopy is a well-defined immune phenotype that is reported to be a risk factor for asthma. Among the many loci that contribute to a genetic predisposition to asthma, the cysteinyl leukotriene receptor genes and their variants have been important subjects of study because they are functionally and...
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