Article
Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort.
The Journal of allergy and clinical immunology - 1 Sept 2009
Duroudier Nathalie P, Strachan David P, Blakey John D, Hall Ian P
Abstract excerpt
BACKGROUND: Cysteinyl leukotrienes (CysLTs) play an important role in the pathophysiology of many allergic inflammatory disorders. However, data on the contribution of genetic variability of the cysteinyl leukotriene receptor 1 gene (CYSLTR1) in asthma and atopy remain conflicting. OBJECTIVE: We investigated the association of polymorphisms of interest located at this locus and allergic disease prevalence in a...
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