Article
Detection of p53 codon 249 mutation in Nigerian patients with hepatocellular carcinoma using a novel evaluation of cell-free DNA.
Annals of hepatology - 1 Jan 2000
Igetei Rufina, Otegbayo Jesse A, Ndububa Dennis A, Lesi Olufunmilayo A, Anumudu Chiaka I, Hainaut Pierre, Gormally Emmanuelle
Abstract excerpt
OBJECTIVES: This case-control study was done to determine the association and prevalence of p53 codon 249 mutation using cell-free DNA in the plasma of patients with hepatocellular carcinoma (HCC) in South-Western Nigeria. METHOD: Eighty-five adults with HCC and seventy-seven age and gender matched controls without evidence of liver disease or malignancy involving any part of the body, were recruited. Plasma DNA...
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