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Article

Identification of essential components of the S. cerevisiae kinetochore.

Cell - 21 May 1993

Doheny K F, Sorger P K, Hyman A A, Tugendreich S, Spencer F, Hieter P

Abstract excerpt

We have designed and utilized two in vivo assays of kinetochore integrity in S. cerevisiae. One assay detects relaxation of a transcription block formed at centromeres; the other detects an increase in the mitotic stability of a dicentric test chromosome. ctf13-30 and ctf14-42 were identified as putative kinetochore mutants by both assays. CTF14 is identical to NDC10/CBF2, a recently identified essential gene...

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Identifiers

PMID: 8500169
DOI: 10.1016/0092-8674(93)90255-o
PMCID: PMC7126583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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