Acquisition of a tumorigenic phenotype by a rat ventral prostate epithelial cell line expressing a transfected activated neu oncogene.

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Article

Acquisition of a tumorigenic phenotype by a rat ventral prostate epithelial cell line expressing a transfected activated neu oncogene.

Cancer research - 1 Jun 1992

Sikes R A, Chung L W

Abstract excerpt

The neu oncogene has been demonstrated to be a potent transforming gene in rodent fibroblasts. The overexpression of the human erbB-2/neu oncogene has been implicated in the development and/or prognosis of several human carcinomas including that of the prostate. To assess the transforming potenti...

Topics

3T3 Cells
Animals
Base Sequence
Blotting, Southern
Cell Line
Cell Transformation, Neoplastic
Epithelium
Gene Expression Regulation
Humans
Male
Mice
Molecular Sequence Data
Oligodeoxyribonucleotides
Oncogenes
Phenotype
Polymerase Chain Reaction
Prostate
Prostatic Neoplasms

Source

Open in PubMed

Identifiers

PMID: 1350510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1350510-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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