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Article

Partial reversion of transformed phenotype of B104 cancer cells by antisense nucleic acids.

Cancer letters - 15 Apr 1993

Shaw Y T, Chang S H, Chiou S T, Chang W C, Lai M D

Abstract excerpt

We used antisense RNA to inhibit the expression of oncogene neu and investigated the effects of diminished neu expression on the phenotypes of B104 cells containing activated oncogene neu. Antisense MT-neu and pSV-neo plasmids were cotransfected into neuroblastoma B104 cells. Southern analysis showed the integration of anti-neu DNA into B104 cells. The expression of neu was inhibited up to 90% as quantitated by...

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PMID: 8097670
DOI: 10.1016/0304-3835(93)90028-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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