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Article

Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome.

Oncogene - 1 Nov 1992

Baird P N, Groves N, Haber D A, Housman D E, Cowell J K

Abstract excerpt

Individuals with constitutional, heterozygous deletions of chromosome region 11p13 are predisposed to the development of Wilms' tumour, indicating the site of the tumour predisposition gene. The WT1 gene is a candidate for this cancer predisposition gene. If this gene is truly involved in tumorigenesis it would be expected to be mutant in tumour tissue from patients with 11p13 deletions. We have used...

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PMID: 1331933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of mutations in the WT1 gene in tumours from patients with the WAGR syndrome.PMID 1331933Read ↗

Insertional inactivation of the WT1 gene in tumour cells from a patient with WAGR syndrome.Semantic proximity Read ↗

Constitutional and somatic mutations in the WT1 gene in Wilms' tumor patients.Semantic proximity Read ↗

Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene.Semantic proximity Read ↗

Homozygous inactivation of WT1 in a Wilms' tumor associated with the WAGR syndrome.Semantic proximity Read ↗

Familial predisposition to Wilms tumor does not segregate with the WT1 gene.Semantic proximity Read ↗

Exclusion of the Wilms tumour gene (WT1) promoter as a site of frequent mutation in Wilms tumour.Semantic proximity Read ↗

Constitutional WT1 mutations in Wilms' tumor patients.Semantic proximity Read ↗

The role of WT1 in Wilms tumorigenesis.Semantic proximity Read ↗

Infrequent mutation of the WT1 gene in 77 Wilms' Tumors.Semantic proximity Read ↗

The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient.Semantic proximity Read ↗

Mutations in the Wilms' tumor gene WT1 in leukemias.Semantic proximity Read ↗

Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome.Semantic proximity Read ↗

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