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Article

Familial predisposition to Wilms tumor does not segregate with the WT1 gene.

Genomics - 1 Aug 1991

Schwartz C E, Haber D A, Stanton V P, Strong L C, Skolnick M H, Housman D E

Abstract excerpt

Wilms tumor (WT) is one of the more common childhood cancers. A small fraction of WT occurs in association with aniridia, genitourinary abnormalities and mental retardation, the WAGR syndrome, and these cases often are accompanied by a constitutional deletion of all or part of band 11p13. Recently a WT susceptibility gene (WT1), localized to 11p13, has been isolated and shown to be inactivated in some sporadic...

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Identifiers

PMID: 1655633
DOI: 10.1016/0888-7543(91)90181-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Familial predisposition to Wilms tumor does not segregate with the WT1 gene.PMID 1655633Read ↗

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Frequency of WT1 and 11p15 constitutional aberrations and phenotypic correlation in childhood Wilms tumour patients.Semantic proximity Read ↗

WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour.Semantic proximity Read ↗

A new familial cancer syndrome including predisposition to Wilms tumor and neuroblastoma.Semantic proximity Read ↗

The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient.Semantic proximity Read ↗

Constitutional and somatic mutations in the WT1 gene in Wilms' tumor patients.Semantic proximity Read ↗

Insertional inactivation of the WT1 gene in tumour cells from a patient with WAGR syndrome.Semantic proximity Read ↗

Genetic and epigenetic alterations on the short arm of chromosome 11 are involved in a majority of sporadic Wilms' tumours.Semantic proximity Read ↗

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor.Semantic proximity Read ↗

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