Familial predisposition to Wilms tumor does not segregate with the WT1 gene.

doi:10.1016/0888-7543(91)90181-d

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Article

Familial predisposition to Wilms tumor does not segregate with the WT1 gene.

Genomics - 1 Aug 1991

Schwartz C E, Haber D A, Stanton V P, Strong L C, Skolnick M H, Housman D E

Abstract excerpt

Wilms tumor (WT) is one of the more common childhood cancers. A small fraction of WT occurs in association with aniridia, genitourinary abnormalities and mental retardation, the WAGR syndrome, and these cases often are accompanied by a constitutional deletion of all or part of band 11p13. Recentl...

Topics

Alleles
Child, Preschool
Chromosome Banding
Chromosomes, Human, Pair 11
Female
Genetic Predisposition to Disease
Humans
Karyotyping
Kidney Neoplasms
Lymphocytes
Male
Pedigree
Polymorphism, Genetic
Wilms Tumor

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