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The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient.

Human molecular genetics - 1 Sept 1994

Pritchard-Jones K, Renshaw J, King-Underwood L

Abstract excerpt

The Wilms tumour (WT1) gene was first localized through its deletion in individuals with the WAGR syndrome (Wilms tumour, aniridia, genitourinary abnormalities and mental retardation). Such individuals have a 30-50% lifetime risk of developing Wilms tumour and carry constitutional interstitial deletions of chromosome 11p13, including the WT1 gene. Second primary tumours occurring in such individuals might also be...

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PMID: 7833922
DOI: 10.1093/hmg/3.9.1633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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