Article
Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).
The Journal of experimental medicine - 1 Oct 1992
Ciccone E, Pende D, Viale O, Than A, Di Donato C, Orengo A M, Biassoni R, Verdiani S, Amoroso A, Moretta A
Abstract excerpt
This study was designed to identify the target molecules of the natural killer (NK) cell-mediated recognition of normal allogeneic target cells. As previously shown, the gene(s) governing the first NK-defined allospecificity (specificity 1) were found to be localized in the major histocompatibility complex region between BF gene and HLA-A. In addition, the analysis of a previously described family revealed that a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.