Article
NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.
The Journal of experimental medicine - 1 Aug 1994
Litwin V, Gumperz J, Parham P, Phillips J H, Lanier L L
Abstract excerpt
Natural killer (NK) cells kill normal and transformed hematopoietic cells that lack expression of major histocompatibility complex (MHC) class I antigens. Lysis of HLA-negative Epstein Barr virus-transformed B lymphoblastoid cell lines (B-LCL) by human NK cell clones can be inhibited by transfect...
Topics
- Alleles
- Antibodies, Monoclonal
- B-Lymphocytes
- HLA-B Antigens
- Humans
- Killer Cells, Natural
- Polymorphism, Genetic
- Receptors, Immunologic
- Receptors, KIR
- Receptors, KIR3DL1
- Transfection