Article
Class I-induced resistance to natural killing: identification of nonpermissive residues in HLA-A2.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1991
Storkus W J, Salter R D, Alexander J, Ward F E, Ruiz R E, Cresswell P, Dawson J R
Abstract excerpt
Structural characteristics of major histocompatibility complex class I antigens associated with natural killer (NK)-resistance phenomena were examined. Previous research has shown that transfection of class I genomic DNA clones into class I-deficient, NK-sensitive target cell lines results in tra...
Topics
- Alleles
- Antibodies, Monoclonal
- Cell Line
- Cloning, Molecular
- Cytotoxicity, Immunologic
- Fluorescent Antibody Technique
- HLA-A2 Antigen
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Killer Cells, Natural
- Male
- Mutagenesis, Site-Directed
- Phenotype