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Article

A novel role for MHC class II antigens: evidence implicating a protective effect on tumour cells against cytotoxicity by NK and LAK cells.

Immunology - 1 Oct 1994

Lobo P I, Patel H C

Abstract excerpt

There are several lines of evidence clearly demonstrating that major histocompatibility complex (MHC) class I antigens are important in protecting haemopoietic tumour cells from natural killer (NK)-mediated cell lysis. In the present studies we examined the role of MHC class II antigens in affording such protection to haemopoietic tumour cell lines. NK and lymphokine-activated killer (LAK) lysis were performed on...

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Topics

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Share to Antigens, Neoplasm
Share to Cytotoxicity, Immunologic
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-D Antigens

Share to Killer Cells, Natural

Share to Lymphoma, B-Cell

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Share to Tumor Cells, Cultured

Source

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Identifiers

PMID: 7835941
PMCID: PMC1414956

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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