Article
Differences in specificity of "DPw2-specific" cytotoxic T cell clones revealed with HLA-mutant lines: evidence that non-DP HLA genes influence recognition by some clones.
European journal of immunology - 1 Mar 1990
Sánchez Pérez M, Diez Orejas R, Petersen J W, De Mars R, Shaw S
Abstract excerpt
Seven allospecific cytotoxic T lymphocyte (CTL) clones derived from DPw2-specific bulk populations were characterized by three approaches to obtain a more detailed understanding of the T cell recognition of the HLA-DPw2 molecule. All seven of the clones were DPw2 specific and indistinguishable in...
Topics
- Antibodies, Monoclonal
- Clone Cells
- Cytotoxicity, Immunologic
- Genes
- Genes, MHC Class II
- Genes, Regulator
- HLA-DP Antigens
- HLA-DR Antigens
- Humans
- Immunity, Cellular
- In Vitro Techniques
- Mutation
- T-Lymphocytes, Cytotoxic