Individual NK cell clones lyse both tumor cell targets and herpes simplex virus-infected fibroblasts in the absence of interferon.

doi:10.1089/vim.1990.3.217

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Article

Individual NK cell clones lyse both tumor cell targets and herpes simplex virus-infected fibroblasts in the absence of interferon.

Viral immunology - 1 Jan 1990

Canessa A, Chatterjee S, Whitley R J, Prasthofer E F, Grossi C E, Tilden A B

Abstract excerpt

The target specificity of natural killer (NK) cells for either tumor cells or virus-infected cells has been investigated. Lymphocyte clones with the surface phenotype of NK cells (CD3-, CD16+) were obtained by limiting dilution of peripheral blood mononuclear cells stimulated with PHA, Herpes sim...

Topics

Adult
Antigens, Surface
Cell Line, Transformed
Clone Cells
Cytotoxicity, Immunologic
Fibroblasts
Herpes Simplex
Herpes Zoster
Humans
Interferons
Interleukin-2
Killer Cells, Natural

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Phenotype

Phytohemagglutinins

Recombinant Proteins

Simplexvirus

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1701642
DOI: 10.1089/vim.1990.3.217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1701642-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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