Article
Clinicopathologic correlates of loss of heterozygosity in Wilm's tumor: a preliminary analysis.
Medical and pediatric oncology - 1 Nov 1996
Grundy P, Telzerow P, Moksness J, Breslow N E
Abstract excerpt
Wilms' tumor-specific loss of heterozygosity (LOH) for DNA markers located at chromosomes 11p13, 11p15, 16q, and 1p has been reported to occur in a minority of Wilms' tumors. We hypothesized that tumors classified by region of LOH would exhibit specific clinicopathologic patterns. We have therefore determined the constitutional and tumor genotypes for markers at 11p13, 11p15, 16q, and 1p in a large series of...
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