Article
Clinicopathologic correlates of loss of heterozygosity in Wilm's tumor: a preliminary analysis.
Medical and pediatric oncology - 1 Nov 1996
Grundy P, Telzerow P, Moksness J, Breslow N E
Abstract excerpt
Wilms' tumor-specific loss of heterozygosity (LOH) for DNA markers located at chromosomes 11p13, 11p15, 16q, and 1p has been reported to occur in a minority of Wilms' tumors. We hypothesized that tumors classified by region of LOH would exhibit specific clinicopathologic patterns. We have therefo...
Topics
- Age Factors
- Anaplasia
- Child, Preschool
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 16
- DNA
- Disease-Free Survival
- Gene Deletion
- Genes, Wilms Tumor
- Genotype
- Heterozygote
- Humans
- Incidence
- Kidney Neoplasms
- Phenotype
- Survival Rate
- Treatment Outcome