Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour.

doi:10.1038/bjc.1998.651

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Article

Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour.

British journal of cancer - 1 Nov 1998

Grundy R G, Pritchard J, Scambler P, Cowell J K

Abstract excerpt

To establish whether loss of heterozygosity (LOH) for chromosome 16q in Wilms' tumours confers an adverse prognosis, DNA from 40 Wilms' tumour/normal pairs were analysed using highly polymorphic microsatellite markers along the length of 16q. Fifteen per cent of tumours showed LOH for 16q. Althou...

Topics

Alleles
Chromosomes, Human, Pair 16
Female
Humans
Loss of Heterozygosity
Male
Prognosis
Wilms Tumor

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