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Article

Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour.

British journal of cancer - 1 Nov 1998

Grundy R G, Pritchard J, Scambler P, Cowell J K

Abstract excerpt

To establish whether loss of heterozygosity (LOH) for chromosome 16q in Wilms' tumours confers an adverse prognosis, DNA from 40 Wilms' tumour/normal pairs were analysed using highly polymorphic microsatellite markers along the length of 16q. Fifteen per cent of tumours showed LOH for 16q. Although the common region of allele loss spanned the 16q24-qter region, a second distinct region of LOH was identified in...

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Identifiers

PMID: 9820177
DOI: 10.1038/bjc.1998.651
PMCID: PMC2063011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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