Reduced virulence of a Listeria monocytogenes phospholipase-deficient mutant obtained by transposon insertion into the zinc metalloprotease gene.

doi:10.1128/iai.60.3.916-921.1992

Back to search

Article

Reduced virulence of a Listeria monocytogenes phospholipase-deficient mutant obtained by transposon insertion into the zinc metalloprotease gene.

Infection and immunity - 1 Mar 1992

Raveneau J, Geoffroy C, Beretti J L, Gaillard J L, Alouf J E, Berche P

Abstract excerpt

A phospholipase-deficient mutant, termed JL762, was obtained from a virulent strain of Listeria monocytogenes by screening a bank of 5,000 Tn1545 transposon-induced mutants on 2.5% egg yolk brain heart infusion agar. As previously shown (J. Mengaud, C. Geoffroy, and P. Cossart, Infect. Immun. 59:...

Topics

Animals
Blotting, Western
DNA Transposable Elements
Female
Listeria monocytogenes
Metalloendopeptidases
Mice
Mice, Inbred ICR
Mutation
Phospholipases
Rabbits
Virulence
Zinc

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.