Article
Aminopeptidase T of M29 Family Acts as A Novel Intracellular Virulence Factor for Listeria monocytogenes Infection.
Scientific reports - 27 Nov 2015
Cheng Changyong, Wang Xiaowen, Dong Zhimei, Shao Chunyan, Yang Yongchun, Fang Weihuan, Fang Chun, Wang Hang, Yang Menghua, Jiang Lingli, Zhou Xiangyang, Song Houhui
Abstract excerpt
The foodborne pathogen Listeria monocytogenes employs a number of virulence determinants including metalloproteases to infect hosts. Here for the first time, we identified an M29 family aminopeptidase T (encoded by lmo1603) from L. monocytogenes that possesses a typical feature to catalyze the cleavage of amino acids from peptide substrates, with a preference for arginine. The purified recombinant Lmo1603 was...
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