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Article

LPS-hyporesponsiveness of mnd mice is associated with a mutation in Toll-like receptor 4.

Genes and immunity - 1 Feb 2001

Bihl F, Larivière L, Qureshi S T, Flaherty L, Malo D

Abstract excerpt

Toll-like receptors (Tlrs) are transmembrane proteins that have recently been shown to play a critical role in the innate immune recognition of microbial constituents. Among this family, Tlr4 is a crucial signal transducer for lipopolysaccharide (LPS), the major component of the Gram-negative bacteria outer cell membrane. In this paper, we report that C57BL/6.KB2-mnd mice, a model of neuronal ceroid...

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PMID: 11294571
DOI: 10.1038/sj.gene.6363732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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