Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O.

doi:10.1111/j.1365-2958.1990.tb00578.x

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Article

Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O.

Molecular microbiology - 1 Dec 1990

Michel E, Reich K A, Favier R, Berche P, Cossart P

Abstract excerpt

Listeriolysin O (LLO), a major virulence factor of the intracellular bacterium Listeria monocytogenes, shares with other known 'thiol-activated toxins' a conserved undecapeptide, ECTGLAWEWWR, located in the C-terminal region of the protein and containing the unique cysteine of the molecule. Singl...

Topics

Alleles
Amino Acid Sequence
Animals
Bacterial Toxins
Base Sequence
Blotting, Southern
Cysteine
DNA Transposable Elements
DNA, Bacterial
Female
Genes, Bacterial
Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hemolysin Proteins

Hydrogen-Ion Concentration

Listeria monocytogenes

Listeriosis

Mice

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 1965218
DOI: 10.1111/j.1365-2958.1990.tb00578.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1965218-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O.PMID 1965218Read ↗

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