Article
The host response to Listeria monocytogenes mutants defective in genes encoding phospholipases C (plcA, plcB) and actin assembly (actA).
Microbiology and immunology - 1 Jan 1997
Rudnicka W, Kaczmarek M, Szeliga J, Germann T, Wieckowska M, Rózalska B
Abstract excerpt
Several genes involved in the determination of Listeria monocytogenes pathogenesis have been identified. Among them, plcA gene encodes phosphatidylinositol-specific phospholipase C (PI-PLC), plcB gene encodes a broad-range phospholipase C (PC-PLC), and actA encodes a protein contributing to actin...
Topics
- Actins
- Animals
- Cells, Cultured
- Dose-Response Relationship, Immunologic
- Escherichia coli
- Female
- Genes, Bacterial
- Interleukin-12
- Lipopolysaccharides
- Listeria monocytogenes
- Listeriosis
- Lymphocyte Activation
- Macrophages, Peritoneal
- Mice
- Mice, Inbred BALB C
- Mutation
- Phagocytosis
- Phosphatidylinositols