Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos.

doi:10.1006/dbio.1994.1019

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Article

Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos.

Developmental biology - 1 Jan 1994

Kispert A, Herrmann B G

Abstract excerpt

The murine Brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in notochord differentiation and posterior mesoderm formation, but make anterior mesoderm. Posterior axial development requires increasing T activi...

Topics

Animals
Base Sequence
Cell Nucleus
DNA-Binding Proteins
Embryo, Mammalian
Embryonic and Fetal Development
Female
Fetal Proteins
Immunohistochemistry
Mice
Molecular Sequence Data
Mutation
Pregnancy
T-Box Domain Proteins
Brachyury Protein

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