Article
Use of chimeras to study gene function in mesodermal tissues during gastrulation and early organogenesis.
Ciba Foundation symposium - 1 Jan 1992
Beddington R S, Püschel A W, Rashbass P
Abstract excerpt
The origin of different mesodermal tissues during gastrulation and the developmental lability of mesodermal precursors can be mapped by transplanting marked epiblast cells to the same or a different position in a host egg cylinder, and assessing the subsequent fate of transplanted tissue. This information provides the context for assessing the role of particular patterns of gene expression during mesoderm...
Topics
- Animals
- Cell Differentiation
- Chimera
- Embryonic and Fetal Development
- Gastrula
- Gene Expression
- Mesoderm
- Mice
- Mutation