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Article

Haplogroup analysis of the risk associated with APOE promoter polymorphisms (-219T/G, -491A/T and -427T/C) in Colombian Alzheimer's disease patients.

Neuroscience letters - 9 Oct 2003

Parra-Bonilla Glenda, Arboleda Gonzalo, Yunis Juan, Solano Eugenia, Pardo Rodrigo, Arango Gabriel, Hedmont Daniel, Arboleda Humberto

Abstract excerpt

Results analyzing the association between polymorphisms in the promoter region of the apolipoprotein E (APOE) gene and Alzheimer's disease (AD) are contradictory. We studied the association of three polymorphisms in the APOE promoter (-219T/G, -491A/T and -427T/C) with AD in a sample of the Colombian population. The polymorphism -491A/T confers increased risk for AD associated with AA genotype independent of...

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Source

Identifiers

PMID: 12951193
DOI: 10.1016/s0304-3940(03)00816-4

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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