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Article

APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals.

Archives of neurology - 1 Sept 2004

Tycko Benjamin, Lee Joseph H, Ciappa Alejandra, Saxena Anjana, Li Chi-Ming, Feng Lin, Arriaga Alex, Stern Yaakov, Lantigua Rafael, Shachter Neil, Mayeux Richard

Abstract excerpt

BACKGROUND: The APOE epsilon4 allele is a genetic risk factor for Alzheimer disease (AD), though the strength of the association varies by ethnic group. Polymorphisms in regulatory sequences of APOE have also been related to AD, but the effects are inconsistent across studies. METHODS: We examine...

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Source

Identifiers

PMID: 15364690
DOI: 10.1001/archneur.61.9.1434

Genes

APOE
APOC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15364690-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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