Article
ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C.
Proceedings of the National Academy of Sciences of the United States of America - 19 Aug 2003
Ben-Aroya Shay, Koren Amnon, Liefshitz Batia, Steinlauf Rivka, Kupiec Martin
Abstract excerpt
Many overlapping surveillance and repair mechanisms operate in eukaryotic cells to ensure the stability of the genome. We have screened to isolate yeast mutants exhibiting increased levels of recombination between repeated sequences. Here we characterize one of these mutants, elg1. Strains lacking Elg1p exhibit elevated levels of recombination between homologous and nonhomologous chromosomes, as well as between...
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