Article
Saccharomyces cerevisiae C1D is implicated in both non-homologous DNA end joining and homologous recombination.
Molecular microbiology - 1 Nov 2002
Erdemir Tuba, Bilican Bilada, Cagatay Tolga, Goding Colin R, Yavuzer Ugur
Abstract excerpt
C1D is a gamma-irradiation inducible nuclear matrix protein that interacts with and activates the DNA-dependent protein kinase (DNA-PK) that is essential for the repair of the DNA double-strand breaks and V(D)J recombination. Recently, it was demonstrated that C1D can also interact with TRAX and prevent the association of TRAX with Translin, a factor known to bind DNA break-point junctions, and that over...
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