Article
The CHL 1 (CTF 1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2/M.
The EMBO journal - 1 Dec 1990
Gerring S L, Spencer F, Hieter P
Abstract excerpt
We have analyzed the CTF1 gene, identified in a screen for mutants with decreased chromosome transmission fidelity and shown to correspond to the previously identified chl1 mutation. Chl1 null mutants exhibited a 200-fold increase in the rate of chromosome III missegregation per cell division, an...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cell Cycle
- Chromosomal Proteins, Non-Histone
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genetic Markers
- Molecular Sequence Data
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Nucleic Acid