Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased genome instability and telomere length in the elg1-deficient Saccharomyces cerevisiae mutant are regulated by S-phase checkpoints.

Eukaryotic cell - 1 Dec 2004

Banerjee Soma, Myung Kyungjae

Abstract excerpt

Gross chromosomal rearrangements (GCRs) are frequently observed in cancer cells. Abnormalities in different DNA metabolism including DNA replication, cell cycle checkpoints, chromatin remodeling, telomere maintenance, and DNA recombination and repair cause GCRs in Saccharomyces cerevisiae. Recently, we used genome-wide screening to identify several genes the deletion of which increases GCRs in S. cerevisiae....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Helicases
Share to Genome, Fungal
Share to Genomic Instability

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methyl Methanesulfonate

Share to Mutagens

Share to S Phase

Share to Telomere

Share to Telomere-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15590829
DOI: 10.1128/EC.3.6.1557-1566.2004
PMCID: PMC539025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased genome instability and telomere length in the elg1-deficient Saccharomyces cerevisiae mutant are regulated by S-phase checkpoints.PMID 15590829Read ↗

ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C.Semantic proximity Read ↗

Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae.Semantic proximity Read ↗

Role of Elg1 protein in double strand break repair.Semantic proximity Read ↗

The ELG1 clamp loader plays a role in sister chromatid cohesion.Semantic proximity Read ↗

Identification of different classes of genome instability suppressor genes through analysis of DNA damage response markers.Semantic proximity Read ↗

Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae.Semantic proximity Read ↗

Spontaneous chromosome loss in Saccharomyces cerevisiae is suppressed by DNA damage checkpoint functions.Semantic proximity Read ↗

DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures.Semantic proximity Read ↗

Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae.Semantic proximity Read ↗

Rif1 and Exo1 regulate the genomic instability following telomere losses.Semantic proximity Read ↗

Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genomic stability disorders: from budding yeast to humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.