Article
Role of Elg1 protein in double strand break repair.
Nucleic acids research - 1 Jan 2007
Ogiwara Hideaki, Ui Ayako, Enomoto Takemi, Seki Masayuki
Abstract excerpt
The inaccurate repair of DNA double-strand breaks (DSBs) can result in genomic instability, and additionally cell death or the development of cancer. Elg1, which forms an alternative RFC-like complex with RFC2-5, is required for the maintenance of genome stability in Saccharomyces cerevisiae, and its function has been linked to DNA replication or damage checkpoint response. Here, we show that Elg1 is involved in...
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