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Article

Thrombomodulin gene polymorphisms and haplotypes and the risk of cardiovascular events: a prospective follow-up study.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2006

Auro K, Komulainen K, Alanne M, Silander K, Peltonen L, Perola M, Salomaa V

Abstract excerpt

BACKGROUND: Thrombomodulin is an anticoagulant expressed during endothelial activation and damage. To address the potential role of allelic variants of thrombomodulin gene in the pathogenesis of cardiovascular diseases, we analyzed in a prospective follow-up study 8 single-nucleotide polymorphisms (SNPs) across the thrombomodulin locus, covering all common (>5%) haplotypes. METHODS AND RESULTS: Two separate,...

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Identifiers

PMID: 16456088
DOI: 10.1161/01.ATV.0000208365.45200.41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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