Article
Association of the single-nucleotide polymorphism and haplotype of the P-selectin gene with ischemic stroke.
Journal of thrombosis and thrombolysis - 1 Jan 2009
Wei Ye-Sheng, Lan Yan, Huang Rui-Ya, Liu Yun-Guang, Tang Ren-Guang, Xu Qun-Qing, Meng Lan-Qing
Abstract excerpt
Inflammation has recently proven to be associated with the pathogenesis of atherosclerosis and inflammatory genes are good candidates for the risk of developing atherosclerosis. The early phase of atherosclerosis involves the recruitment of inflammatory cells from the circulation and their transendothelial migration. This process is mainly mediated by cellular adhesion molecules. The adhesion molecule P-selectin...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Brain Ischemia
- China
- Comorbidity
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Humans
