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Article

Transitional B cells: step by step towards immune competence.

Trends in immunology - 1 Jun 2003

Chung James B, Silverman Michael, Monroe John G

Abstract excerpt

Transitional B cells mark the crucial link between bone-marrow (BM) immature and peripheral mature B cells. Examination reveals unexpected heterogeneity, consisting of contiguous subsets with phenotypic and functional differences. Data point to the late transitional B-cell stage as a crucial juncture at which developing B cells gain access to splenic follicles, become responsive to T-cell help and lose...

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Source

Identifiers

PMID: 12810111
DOI: 10.1016/s1471-4906(03)00119-4

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transitional B cells: step by step towards immune competence.PMID 12810111Read ↗

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Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation.Semantic proximity Read ↗

The pre-B cell receptor checkpoint.Semantic proximity Read ↗

Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement.Semantic proximity Read ↗

Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation.Semantic proximity Read ↗

The influence of developmental timing on B cell diversity.Semantic proximity Read ↗

B cell development and its deregulation to transformed states at the pre-B cell receptor-expressing pre-BII cell stage.Semantic proximity Read ↗

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