Article
Therapeutic implications of advances in our understanding of transitional B-cell development in humans.
Expert review of clinical immunology - 1 Sept 2010
Suryani Santi, Tangye Stuart G
Abstract excerpt
B-cell development is characterized by the progressive maturation of hematopoietic stem cells through several stages to ultimately give rise to the mature B-cell pool that has been selected for reactivity against non-self antigens. Thus, the mature pool of naive B cells is capable of elicting hig...
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