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Article

Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation.

The Journal of experimental medicine - 21 Jan 2008

Meyer-Bahlburg Almut, Andrews Sarah F, Yu Karl O A, Porcelli Steven A, Rawlings David J

Abstract excerpt

We have characterized a distinct, late transitional B cell subset, CD21(int) transitional 2 (T2) B cells. In contrast to early transitional B cells, CD21(int) T2 B cells exhibit augmented responses to a range of potential microenvironmental stimuli. Adoptive transfer studies demonstrate that this subset is an immediate precursor of both follicular mature and marginal zone (MZ) B cells. In vivo, a large percentage...

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Source

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Identifiers

PMID: 18180309
DOI: 10.1084/jem.20071088
PMCID: PMC2234381

Genes

BCR
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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