Article
Novel human transitional B cell populations revealed by B cell depletion therapy.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 2009
Palanichamy Arumugam, Barnard Jennifer, Zheng Bo, Owen Teresa, Quach Tam, Wei Chungwen, Looney R John, Sanz Iñaki, Anolik Jennifer H
Abstract excerpt
Transitional cells represent a crucial step in the differentiation and selection of the mature B cell compartment. Human transitional B cells have previously been variably identified based on the high level of expression of CD10, CD24, and CD38 relative to mature B cell populations and are expanded in the peripheral blood following rituximab-induced B cell-depletion at reconstitution. In this study, we take...
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