Novel human transitional B cell populations revealed by B cell depletion therapy.

doi:10.4049/jimmunol.0801859

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Article

Novel human transitional B cell populations revealed by B cell depletion therapy.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2009

Palanichamy Arumugam, Barnard Jennifer, Zheng Bo, Owen Teresa, Quach Tam, Wei Chungwen, Looney R John, Sanz Iñaki, Anolik Jennifer H

Abstract excerpt

Transitional cells represent a crucial step in the differentiation and selection of the mature B cell compartment. Human transitional B cells have previously been variably identified based on the high level of expression of CD10, CD24, and CD38 relative to mature B cell populations and are expanded in the peripheral blood following rituximab-induced B cell-depletion at reconstitution. In this study, we take...

Topics

Animals
B-Lymphocyte Subsets
B-Lymphocytes
Cell Differentiation
Flow Cytometry
Humans
Lymphocyte Depletion
Mice
Phenotype
Precursor Cells, B-Lymphoid

Source

Open in PubMed Open full text

Identifiers

PMID: 19414749
DOI: 10.4049/jimmunol.0801859
PMCID: PMC2746373

Genes

ABCB1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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