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Article

The pre-B cell receptor checkpoint.

FEBS letters - 18 Jun 2010

Mårtensson Inga-Lill, Almqvist Nina, Grimsholm Ola, Bernardi Angelina I

Abstract excerpt

B lymphocytes are essential antibody-producing cells of the immune system. During the development of progenitor B cells to mature B cells that express a membrane-bound antibody, the B cell receptor (BCR), the cells undergo selection at several checkpoints, which ensures that a diverse antibody repertoire is generated and that the BCRs recognise foreign-, but not self-, antigens. In this review, we consider the...

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Source

Identifiers

PMID: 20420836
DOI: 10.1016/j.febslet.2010.04.057

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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