Article
The influence of developmental timing on B cell diversity.
Current opinion in immunology - 1 Apr 2018
Kristiansen Trine A, Vanhee Stijn, Yuan Joan
Abstract excerpt
The adult adaptive immune system is comprised of a wide spectrum of lymphocyte subsets with distinct antigen receptor repertoire profiles, effector functions, turnover times and anatomical locations, acting in concert to provide optimal host protection and self-regulation. While some lymphocyte populations are replenished by bone marrow hematopoietic stem cells (HSCs) through adulthood, others emerge during a...
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