Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modified allelic replication in lymphocytes of patients with neurofibromatosis type 1.

Cancer genetics and cytogenetics - 1 Jun 2003

Reish Orit, Orlovski Ana, Mashevitz Maya, Sher Carron, Libman Vitalia, Rosenblat Malka, Avivi Lydia

Abstract excerpt

Transcription activity of genes is related to their replication timing, accordingly gene activation is coupled with a shift from late replication to early replication and vice versa. The relationship between replication timing and gene expression is best manifested by monoallelically expressed genes which show an asynchronous pattern of allelic replication, with the active allele replicating earlier than the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to In Situ Hybridization, Fluorescence

Share to Lymphocytes

Share to Neurofibromatosis 1

Share to Phytohemagglutinins

Source

Identifiers

PMID: 12781447
DOI: 10.1016/s0165-4608(02)00858-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modified allelic replication in lymphocytes of patients with neurofibromatosis type 1.PMID 12781447Read ↗

Modification in the inherent mode of allelic replication in lymphocytes of patients suffering from renal cell carcinoma: a novel genetic alteration associated with malignancy.Semantic proximity Read ↗

Allele-specific replication associated with aneuploidy in blood cells of patients with hematologic malignancies.Semantic proximity Read ↗

Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients.Semantic proximity Read ↗

Replication timing of the various FMR1 alleles detected by FISH: inferences regarding their transcriptional status.Semantic proximity Read ↗

Replication status as a possible marker for genomic instability in cells originating from genotypes with balanced rearrangements.Semantic proximity Read ↗

Temporal differences in replication timing of homologous loci in malignant cells derived from CML and lymphoma patients.Semantic proximity Read ↗

Altered mode of allelic replication accompanied by aneuploidy in peripheral blood lymphocytes of prostate cancer patients.Semantic proximity Read ↗

Asynchronous replication of biallelically expressed loci: a new phenomenon in Turner syndrome.Semantic proximity Read ↗

Coordinated replication timing of monoallelically expressed genes along human autosomes.Semantic proximity Read ↗

Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies <i>MCM10</i> as a novel regulator of the replication programSemantic proximity Read ↗

Chromosomal coordination and differential structure of asynchronous replicating regions.Semantic proximity Read ↗

Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.