Article
Altered mode of allelic replication accompanied by aneuploidy in peripheral blood lymphocytes of prostate cancer patients.
International journal of cancer - 10 Aug 2004
Dotan Zohar A, Dotan Aviva, Ramon Jacob, Avivi Lydia
Abstract excerpt
Replication timing of the genetic material is a highly programmed process correlated with expression, stability and methylation capacity. An important aspect of that timing is the temporal order of allelic replication: a synchronous mode for biallelically expressed genes and an asynchronous for monoallelically expressed genes. Previous studies showed that malignancy is associated with changes in the inherent mode...
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