Article
Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells.
Experimental hematology - 1 Jan 2004
Nagler Arnon, Korenstein-Ilan Avital, Amiel Aliza, Avivi Lydia
Abstract excerpt
OBJECTIVE: Because the effect of granulocyte colony-stimulating factor (G-CSF), which is widely used for allogeneic stem cell transplantation, on DNA function and stability has not yet been unequivocally elucidated, the aim of this study was to determine whether G-CSF leads to epigenetic and/or g...
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