Article
Replication timing of the various FMR1 alleles detected by FISH: inferences regarding their transcriptional status.
Human genetics - 1 Jan 1998
Yeshaya J, Shalgi R, Shohat M, Avivi L
Abstract excerpt
Following the application of two-color fluorescence in-situ hybridization (FISH) to human interphase cells, we examined the replication timing of the fragile-X locus relative to the non-transcribed late replicating alpha-satellite region of chromosome-X, a built-in intracellular reference locus. In this assay, an unreplicated locus is identified by a single hybridization signal (singlet; S), whereas a replicated...
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