Article
Coordinated replication timing of monoallelically expressed genes along human autosomes.
Human molecular genetics - 15 Mar 2004
Ensminger Alexander W, Chess Andrew
Abstract excerpt
A number of genes in the mammalian genome are expressed from only one of two alleles in either an imprinted or random manner. Those belonging to the random class include X-linked genes subject to X inactivation, as well as a number of autosomal genes, including odorant receptors, immunoglobulins, T-cell receptors, interleukins, natural killer-cell receptors and pheromone receptors. Monoallelically expressed genes...
Topics
- Alleles
- Chromosomes, Artificial, Bacterial
- Chromosomes, Human
- DNA Replication
- Dosage Compensation, Genetic
- Fibroblasts
- Genes
- Humans
- In Situ Hybridization, Fluorescence
- Time Factors
- Trisomy