Article
Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.
Diabetes - 1 Jun 2003
Penha-Gonçalves Carlos, Moule Carolyn, Smink Luc J, Howson Joanna, Gregory Simon, Rogers Jane, Lyons Paul A, Suttie Joseph J, Lord Christopher J, Peterson Laurence B, Todd John A, Wicker Linda S
Abstract excerpt
Genes affecting autoimmune type 1 diabetes susceptibility in the nonobese diabetic (NOD) mouse (Idd loci) have been mapped using a congenic strain breeding strategy. In the present study, we used a combination of BAC clone contig construction, polymorphism analysis of DNA from congenic strains, and sequence mining of the human orthologous region to generate an integrated map of the Idd10 region on mouse...
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