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Article

Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse.

Annals of the New York Academy of Sciences - 1 Nov 2003

Ikegami Hiroshi, Fujisawa Tomomi, Makino Susumu, Ogihara Toshio

Abstract excerpt

Inheritance of type 1 diabetes is polygenic with a major susceptibility gene located in the major histocompatibility complex (MHC). In addition to MHC-linked susceptibility, a number of susceptibility genes have been mapped outside the MHC in both humans and animal models. In order to localize and identify susceptibility genes for type 1 diabetes, we have developed a series of congenic strains in which either...

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PMID: 14679059
DOI: 10.1196/annals.1288.026

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Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse.PMID 14679059Read ↗

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