Article
The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes.
Database : the journal of biological databases and curation - 1 Jan 2013
Steward Charles A, Gonzalez Jose M, Trevanion Steve, Sheppard Dan, Kerry Giselle, Gilbert James G R, Wicker Linda S, Rogers Jane, Harrow Jennifer L
Abstract excerpt
Model organisms are becoming increasingly important for the study of complex diseases such as type 1 diabetes (T1D). The non-obese diabetic (NOD) mouse is an experimental model for T1D having been bred to develop the disease spontaneously in a process that is similar to humans. Genetic analysis of the NOD mouse has identified around 50 disease loci, which have the nomenclature Idd for insulin-dependent diabetes,...
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