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Article

The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes.

Database : the journal of biological databases and curation - 1 Jan 2013

Steward Charles A, Gonzalez Jose M, Trevanion Steve, Sheppard Dan, Kerry Giselle, Gilbert James G R, Wicker Linda S, Rogers Jane, Harrow Jennifer L

Abstract excerpt

Model organisms are becoming increasingly important for the study of complex diseases such as type 1 diabetes (T1D). The non-obese diabetic (NOD) mouse is an experimental model for T1D having been bred to develop the disease spontaneously in a process that is similar to humans. Genetic analysis of the NOD mouse has identified around 50 disease loci, which have the nomenclature Idd for insulin-dependent diabetes,...

Topics

Animals
Base Pairing
Base Sequence
Diabetes Mellitus, Type 1
Genetic Loci
Genetic Variation
Genome
Humans
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred NOD

Molecular Sequence Annotation

Polymorphism, Single Nucleotide

Sequence Alignment

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 23729657
DOI: 10.1093/database/bat032
PMCID: PMC3668384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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