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Article

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.

Immunogenetics - 1 Mar 2017

Lin Bixuan, Ciecko Ashley E, MacKinney Erin, Serreze David V, Chen Yi-Guang

Abstract excerpt

Type 1 diabetes (T1D) results from complex interactions between genetic and environmental factors. The nonobese diabetic (NOD) mouse develops spontaneous T1D and has been used extensively to study the genetic control of this disease. T1D is suppressed in NOD mice congenic for the C57BL/10 (B10)-derived Idd9 resistance region on chromosome 4. Previous studies conducted by other investigators have identified four...

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Identifiers

PMID: 27796442
DOI: 10.1007/s00251-016-0957-3
PMCID: PMC5335865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.PMID 27796442Read ↗

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