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Article

Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10.

Biochemical and biophysical research communications - 3 Jun 2005

Yamaji Kaori, Ikegami Hiroshi, Fujisawa Tomomi, Noso Shinsuke, Nojima Koji, Babaya Naru, Itoi-Babaya Michiko, Makino Susumu, Sakamoto Tsutomu, Ogihara Toshio

Abstract excerpt

Among polygenes conferring susceptibility to type 1 diabetes in the NOD mouse, Idd10 on distal chromosome 3 has been shown to be important for disease susceptibility. In this study, we investigated the candidacy of Fcgr1 and Cd101 for Idd10, by congenic mapping and candidate gene sequencing. Among seven NOD-related strains studied, the IIS mouse was found to possess a recombinant Idd10 interval with the same...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15850792
DOI: 10.1016/j.bbrc.2005.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10.PMID 15850792Read ↗

Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse.Semantic proximity Read ↗

Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.Semantic proximity Read ↗

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.Semantic proximity Read ↗

Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.Semantic proximity Read ↗

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.Semantic proximity Read ↗

Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse.Semantic proximity Read ↗

A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility.Semantic proximity Read ↗

Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene.Semantic proximity Read ↗

Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes.Semantic proximity Read ↗

Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci.Semantic proximity Read ↗

Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3.Semantic proximity Read ↗

NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.Semantic proximity Read ↗

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